Search results for "Interleukine 2"

showing 5 items of 5 documents

Updated insights into the mechanism of action and clinical profile of the immunoadjuvant QS-21: A review

2019

Background Vaccine adjuvants are compounds that significantly enhance/prolong the immune response to a co-administered antigen. The limitations of the use of aluminium salts that are unable to elicite cell responses against intracellular pathogens such as those causing malaria, tuberculosis, or AIDS, have driven the development of new alternative adjuvants such as QS-21, a triterpene saponin purified from Quillaja saponaria. Purpose The aim of this review is to attempt to clarify the mechanism of action of QS-21 through either receptors or signaling pathways in vitro and in vivo with special emphasis on the co-administration with other immunostimulants in new adjuvant formulations, called a…

InflammasomesT-Lymphocytesmedicine.medical_treatmentHerpes zosterPharmaceutical ScienceMonophosphoryl Lipid AAPCs antigen presenting cellsMiceCMI cell mediated immunity0302 clinical medicineDrug DiscoveryHerpes Zoster VaccineMedicineNSCLC non small cell lung carcinomaCancerImmunity CellularVaccines Synthetic0303 health sciencesImmunogenicityIl-2 interleukine 2HIV human immunodeficiency virusLipid A030220 oncology & carcinogenesisCytokinesMolecular MedicineDCs dendritic cellsNK natural killerAdjuvantTLR Toll-like receptorHerpes Zoster VaccineCD cluster of differentiationAntigen-Presenting CellsCTL cytotoxic T lymphocytesHZ herpes zosterMPL 3-deacylated monophosphoryl lipidVaccine adjuvantImmunoadjuvantArticleVZV varicella zoster virus03 medical and health sciencesImmune systemAdjuvants ImmunologicAntigenPAMPs pathogen-associated molecular patternsMalaria VaccinesPRRs pathogen recognition receptorsQS-21 Quillaja saponaria Molina-fraction 21AnimalsMHC major histocompatibility complexMtb Mycobacterium tuberculosis bacteriaSARS severe acute respiratory syndromeAntigen-presenting cellIFN-γ interferon-gamma030304 developmental biologyPharmacologybusiness.industryA-β amyloid-betaTNF-α tumor necrosis factor-alphaSaponinsQS-21MalariaQuillaja saponariaComplementary and alternative medicineTCR T-cell receptorLiposomesImmunologyKLH keyhole limpet hemocyaninbusinessdLN draining lymph nodesMAPK mitogen activated protein kinasePhytomedicine
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Human interleukin 2: molecular biology, physiology and clinical possibilities.

1986

Interleukin 2Antigens Differentiation T-Lymphocytemedicine.medical_treatmentT-LymphocytesImmunologyPhysiologyGraft vs Host DiseaseCyclosporinsBiologyInterleukine 2MiceNeoplasmsmedicineImmune ToleranceImmunology and AllergyAnimalsHumansReceptors ImmunologicBone Marrow TransplantationMacrophagesLymphokineImmunization PassiveAntibodies MonoclonalImmunosuppressionReceptors Interleukin-2HematologyImmunotherapyRecombinant ProteinsKiller Cells NaturalImmunologyAntigens SurfaceInterleukin-2medicine.drugImmunobiology
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Development of oil cysts after subcutaneous injection of interferon-α and interleukin-2

2006

Interleukin 2Pathologymedicine.medical_specialtybusiness.industryAlpha interferonDermatologyInterleukine 2Subcutaneous injectionInterferon αToxicityMedicinebusinessInterferon alfamedicine.drugBritish Journal of Dermatology
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2-hydroxy-methyl-1(N-phtaloyltryptophyl) aziridine stimule la prolifération in vitro des lymphocytes humains et la sécrétion des interleukines

2008

Resume But de l’etude Il a ete demontre que les aziridines possedent une activite immunotropique marquee. Dans ce travail, les effets in vitro d’une aziridine nouvellement synthetisee (2-hydroxy-methyl-1(N-phtaloyltryptophyl) aziridine) sont determines sur la proliferation des lymphocytes humains stimules par les agents mitogenes, et sur la secretion des interleukines 2 et 6 (IL-2, IL-6). Materiel et methodes Les lymphocytes du sang peripherique sont isoles par centrifugation differentielle dans un gradient de Ficoll-Paque. Ils sont mis en culture en presence d’agents mitogenes (concanavaline A, lipopolysaccharide) et de differentes concentrations de l’aziridine testee. La determination de …

Interleukin 2biologyChemistrymedicine.medical_treatmentLymphocyteInterleukinGeneral MedicineLymphocyte proliferationMolecular biologyInterleukine 2Cytokinemedicine.anatomical_structuremedicinebiology.proteinInterleukin 6medicine.drugPathologie Biologie
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Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications

1990

(1990). Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications. International Journal of Neuroscience: Vol. 51, No. 3-4, pp. 299-301.

MaleAgingHypothalamo-Hypophyseal SystemGonadotropin RHbusiness.industryGeneral NeurosciencePhosphatidylserinesGeneral MedicinePhosphatidylserineInterleukine 2RatsAntibody productionchemistry.chemical_compoundImmune systemchemistryMemoryImmunologyAnimalsLearningMedicineFemaleProestrusbusinessNeuroscienceReceptors LHRHInternational Journal of Neuroscience
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